New Models of Integrated HIV/AIDS, Addiction, and Primary Care Services (R01 Clinical Trial Required) | PAR 20 273

Opportunity Information: Apply for PAR 20 273

The National Institutes of Health (NIH) funding opportunity announcement (FOA) titled "New Models of Integrated HIV/AIDS, Addiction, and Primary Care Services (R01 Clinical Trial Required)" (Funding Opportunity Number: PAR-20-273; CFDA: 93.279) is a discretionary grant program designed to support research that tests improved, real-world models of care that more effectively combine HIV services, addiction treatment, and primary care. The core goal is to move beyond treating these needs in separate systems by evaluating enhanced, integrated approaches that can deliver coordinated, patient-centered care, particularly for people whose HIV outcomes are affected by substance use disorders and other co-occurring health and social challenges. Because the FOA explicitly requires a clinical trial, applicants are expected to conduct studies that prospectively test an intervention model, not simply describe or observe existing programs.

This opportunity uses the NIH R01 grant mechanism, which typically supports substantial, multi-year research projects. The FOA emphasizes "testing" enhanced models, meaning the focus is on generating rigorous evidence about what works, for whom, and under what conditions, when HIV care, addiction services (such as medication treatment for opioid use disorder, counseling, harm reduction linkages, or other evidence-based supports), and primary care are intentionally integrated. Projects under this FOA would generally be expected to evaluate outcomes relevant to HIV prevention and treatment (for example, engagement in care, adherence, viral suppression, PrEP access where applicable), addiction-related outcomes (for example, initiation and retention in treatment, reduced overdose risk, reduced harmful use), and broader health outcomes typical of primary care integration (for example, management of chronic conditions, preventive services uptake, and continuity of care). Integrated models often also involve practical service delivery changes, such as co-located services, shared care teams, coordinated referrals with warm handoffs, case management, use of peer navigators, telehealth-enabled coordination, or workflow and system redesign to reduce barriers and improve retention across services.

Eligibility is broad and includes many types of domestic U.S. organizations as well as certain non-U.S. entities. Eligible applicants listed in the source include state governments, county governments, city or township governments, special district governments, independent school districts, public and state-controlled institutions of higher education, private institutions of higher education, federally recognized Native American tribal governments, tribal organizations (other than federally recognized tribal governments), public housing authorities and Indian housing authorities, nonprofits with or without 501(c)(3) status (other than institutions of higher education), for-profit organizations other than small businesses, small businesses, and other organizations. The FOA also specifically calls out additional eligible applicants such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), eligible federal agencies, faith-based or community-based organizations, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Indian/Native American tribal governments that are not federally recognized, non-domestic (non-U.S.) entities (foreign organizations), regional organizations, Tribally Controlled Colleges and Universities (TCCUs), and U.S. territories or possessions. This wide eligibility suggests NIH is encouraging participation from academic centers, healthcare and community providers, tribal and territorial entities, and organizations serving populations disproportionately affected by HIV and substance use.

From an administrative standpoint, the FOA was created on 2020-08-28, the original closing date shown is 2023-09-16, and the award ceiling and expected number of awards are not specified in the provided source data. The activity category is listed as Education and Health, reflecting the healthcare research and service-delivery focus. Overall, the announcement is aimed at strengthening evidence for integrated care strategies that can be implemented in routine settings, with the expectation that funded projects will produce actionable findings on how to design, deliver, and sustain integrated HIV, addiction, and primary care services in ways that improve patient outcomes and system performance.

• The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "New Models of Integrated HIV/AIDS, Addiction, and Primary Care Services (R01 Clinical Trial Required)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279.
• This funding opportunity was created on 2020-08-28.
• Applicants must submit their applications by 2023-09-16. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for PAR 20 273

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