Opportunity Information: Apply for RFA CA 17 044
Mechanisms of Cancer Drug Resistance and Sensitivity: Coordinating Center (U24) (RFA-CA-17-044) is a National Institutes of Health cooperative agreement funding opportunity released under the Beau Biden Cancer Moonshot initiative, a federal effort aimed at speeding up progress in cancer research. The grant is designed to create a single Coordinating Center that supports and connects a set of already-funded Drug Resistance and Sensitivity Centers (DRSCs). Those DRSCs were established through an earlier NIH announcement (RFA-CA-17-009) as U54 specialized centers, and they focus on a major scientific priority identified by the Cancer Moonshot Blue Ribbon Panel: building a network of multidisciplinary teams to understand why tumors respond to therapies or become resistant, and to translate those insights into better anti-cancer treatment strategies.
The main goal of this U24 award is not to function as another independent research center competing with the U54s, but to serve as the hub that makes the whole network work as a coordinated program. In practical terms, the Coordinating Center is expected to integrate and facilitate trans-disciplinary collaboration across all participating DRSCs. That means helping the centers work together more efficiently, aligning approaches where appropriate, supporting cross-center communication, and making it easier to combine, compare, and synthesize results so the network produces more than the sum of its parts. A core emphasis is integration: ensuring that findings coming from different scientific angles, data types, model systems, or experimental platforms can be brought together into a coherent picture of drug resistance and sensitivity mechanisms.
Because this is a cooperative agreement, NIH anticipates substantial federal involvement in the direction and oversight of the work. The Coordinating Center is therefore expected to operate in close coordination with NIH program leadership and with the U54 DRSC investigators. The intent is to accelerate progress by reducing fragmentation across centers, promoting consistent practices when useful (for example, around how data or results are shared), and creating the infrastructure and coordination needed for rapid communication, joint problem-solving, and network-wide planning.
The opportunity is offered by the U.S. Department of Health and Human Services through the National Institutes of Health, and it sits in the health and education funding activity space. The catalog listing includes CFDA numbers 93.353, 93.394, and 93.395. Eligibility is broad and includes state and local governments, public and private institutions of higher education, nonprofits (including both 501(c)(3) and non-501(c)(3) organizations), for-profit organizations other than small businesses, and small businesses, with additional eligibility details referenced in the announcement text. NIH expected to make one award under this FOA, with an award ceiling of $350,000. The FOA was created on October 20, 2017, with an original closing date of January 5, 2018.
Overall, this announcement funds a single coordination-focused institution or organization to act as the connective tissue for a national research network investigating cancer therapy response and resistance. The federal goal is to speed discovery and translation by ensuring that the specialized DRSCs can collaborate smoothly, share insights and outputs effectively, and produce integrated results that better inform the development of innovative strategies to prevent, overcome, or exploit drug resistance in cancer.Apply for RFA CA 17 044
- The Department of Health and Human Services, National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Mechanisms of Cancer Drug Resistance and Sensitivity: Coordinating Center (U24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.353, 93.394, 93.395.
- This funding opportunity was created on Oct 20, 2017.
- Applicants must submit their applications by Jan 05, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $350,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments, County governments, Public and State controlled institutions of higher education, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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| Revisions for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (P01 Clinical Trials Optional) Apply for RFA CA 18 009 Funding Number: RFA CA 18 009 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $150,000 |
| Revisions for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (P50 Clinical Trials Optional) Apply for RFA CA 18 010 Funding Number: RFA CA 18 010 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $150,000 |
| Revisions for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (U54 Clinical Trials Optional) Apply for RFA CA 18 008 Funding Number: RFA CA 18 008 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $150,000 |
| Revisions for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (U01 Clinical Trials Optional) Apply for RFA CA 18 007 Funding Number: RFA CA 18 007 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $150,000 |
| Revisions for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (R01 Clinical Trials Optional) Apply for RFA CA 18 006 Funding Number: RFA CA 18 006 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $150,000 |
| NIDA Translational Avant-Garde Award for Development of Medication to Treat Substance Use Disorders (UG3/UH3, Clinical Trial Optional) Apply for RFA DA 18 020 Funding Number: RFA DA 18 020 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $1,000,000 |
| Administrative Supplements to NCI Grant and Cooperative Agreement Awards to Support Collaborations with the PDX Development and Trial Centers Research Network (PDXNet)(Admin Suppl - Clinical Trial Not Allowed) Apply for PA 18 496 Funding Number: PA 18 496 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $125,000 |
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| NCI Community Oncology Research Program (NCORP) Community Sites (UG1 Clinical Trial Required) Apply for RFA CA 18 016 Funding Number: RFA CA 18 016 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| NCI Community Oncology Research Program (NCORP) Minority/Underserved Community Sites (UG1 Clinical Trial Required) Apply for RFA CA 18 017 Funding Number: RFA CA 18 017 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| NCI Community Oncology Research Program (NCORP) Research Bases (UG1 Clinical Trial Required) Apply for RFA CA 18 015 Funding Number: RFA CA 18 015 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
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