DoD PRMRP Investigator-Initiated Research Award | W81XWH 22 PRMRP IIRA

Opportunity Information: Apply for W81XWH 22 PRMRP IIRA

The DoD PRMRP Investigator-Initiated Research Award (IIRA) is a funding opportunity from the Department of Defense (administered by the U.S. Army Medical Research Acquisition Activity, USAMRAA) meant to support investigator-driven studies that can meaningfully advance research and/or improve patient care for a disease or condition that fits within one of the FY22 PRMRP Topic Areas and aligns with one of the FY22 PRMRP Strategic Goals. The program is designed to let researchers bring forward strong, well-justified ideas that arise from many possible starting points, including laboratory findings, population-based research, clinical observations from direct patient care, or even well-supported anecdotal evidence. A key expectation is that applicants do not propose purely speculative work; proposals must include relevant supporting data that justify the research rationale, and those data can be either unpublished preliminary results or evidence drawn from the scientific literature.

A central emphasis of the IIRA is impact. The program is specifically framed to fund work that could generate highly impactful results, such as data that meaningfully shift understanding of a condition, enable critical discoveries, or drive major advances in how a disease is studied or managed. Applications are expected to spell out both short-term and long-term outcomes or products, which may include new knowledge (for example, insights into disease mechanisms or biomarkers) and/or tangible materiel outputs (such as tools, assays, model systems, or other usable research products). Beyond listing deliverables, the proposal needs to clearly connect those expected outputs to a critical problem or unanswered question in the field, and explain why the work matters for the specific PRMRP topic area and strategic goal being addressed.

In terms of scientific scope, the award supports a wide range of research stages, from basic laboratory studies through translational research. This includes preclinical work in animal models, studies involving human subjects, and correlative studies that are tied to an existing clinical trial. However, the IIRA cannot be used to conduct clinical trials themselves. The opportunity does allow non-interventional clinical research, meaning studies that do not assign participants to specific interventions as part of the research (for example, observational studies, analyses of specimens or data, and other non-interventional designs), as long as they fit the program rules.

Administratively, this opportunity was offered under Funding Opportunity Number W81XWH 22 PRMRP IIRA and falls under CFDA 12.420 (science and technology and other research and development). It allows funding through either a grant or a cooperative agreement, and eligibility is described as unrestricted, meaning it is broadly open to many entity types unless additional eligibility clarifications apply in the full announcement. The posting date was March 16, 2022, with an original closing date of May 27, 2022, and the agency anticipated making around 30 awards. The listed award ceiling is shown as 0 in the source record, which often indicates that the maximum amount is defined elsewhere in the full solicitation materials rather than in the summary field.

• The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD PRMRP Investigator-Initiated Research Award" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
• This funding opportunity was created on Mar 16, 2022.
• Applicants must submit their applications by May 27, 2022. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• The number of recipients for this funding is limited to 30 candidate(s).
• Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.

Apply for W81XWH 22 PRMRP IIRA

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